Autotransplantation of Cryopreserved Parathyroid Tissue in Man

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Large fluctuations in parathyroid hormone concentrations after autotransplantation of parathyroid tissue in the forearm.

To the Editor: Hyperparathyroidism is a potentially serious complication in patients with advanced renal insufficiency (1 ). As renal mass dwindles and phosphate excretion gets more difficult, synthesis of 1,25-dihydroxycholecalciferol is impaired, and concentrations of fibroblast growth factor-23 increase (2 ), leading to low serum calcium concentrations and an initially appropriate response o...

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Xenotransplantation of human cryopreserved parathyroid tissue isolated from parathyroid adenomas to normocalcemic rabbits.

OBJECTIVE Parathyroid allotransplantation is a new method for the treatment of permanent hypoparathyrodism. Adenoma cells are not used for transplantation because of the potential for functional or histopathologic transformation. In this study, we transplanted human adenomatous parathyroid cells to rabbits. MATERIAL AND METHODS Parathyroid adenoma tissue taken from a male patient was cryopres...

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Parathyroid autotransplantation in rats having hypoparathyroidism.

Re-implantation techniques of extracted parathyroid tissue were developed in order to prevent temporary hypocalcemia. During thyroid surgery; inadvertently removed or devascularized parathyroid gland is usually implanted in the sternocleidomastoid muscle. In this experimental study using rats with hypoparathyroidism, our aim was to investigate whether the excised parathyroid tissue could be see...

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Parathyroid Autotransplantation During ThyroidectomyIs Frozen Section Necessary?

Results: Of 179 attempted autotransplantations of parathyroid glands, parathyroid tissue was confirmed in 167 biopsy specimens (93.3%). Incorrect identification of parathyroid gland occurred in 12 instances. The tissue mistaken as parathyroid gland included fat in 6 cases, thyroid tissue in 4 cases, lymph node in 1 case, and thymus in 1 case. Transplantation of at least 1 parathyroid gland (ran...

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Intrathymic parathyroid tissue in man: clinical significance and report of a case of intrathymic parathyroid adenoma.

Very little attention has been paid in the past to the intrathymie parathy roid tissue in man. Accessory parathyroid within thymic tissue has already been reported in such mammals as monkeys (Forsyth1), sheep (Mayer2), dogs (Marine3), rabbits (Haberfeld et al4), cats (Farner et al5), and rats (Van Dyke,6 Togofuku7) as well as in reptiles (Dustin et al8). Only a small number of cases have been r...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1979

ISSN: 0003-4932

DOI: 10.1097/00000658-197902000-00002